The Kansas City Chiefs launch their 2025 NFL season on the global stage against the Los Angeles Chargers at Arena Corinthians in São Paulo, Brazil.
Patrick Mahomes and Travis Kelce once again lead a Chiefs squad with Super Bowl ambitions — but this time around, they look to erase the sting of a postseason disappointment.
All eyes will be on Kansas City’s rebuilt offensive line. Rookie left tackle Josh Simmons makes his debut alongside second-year guard Kingsley Suamataia, a duo tasked with protecting Mahomes against a Chargers pass rush that’s long been their calling card.
Los Angeles, meanwhile, turns to its new-look offense, anchored by veteran Justin Herbert and built around second-year wideout Ladd McConkey and rookie running back Omarion Hampton. McConkey returns to action after a breakout rookie campaign, while Hampton brings bruising physicality to the backfield. The Chargers hope this youth movement can keep pace with their perennial division rivals.
The international backdrop adds extra spectacle, capped by a halftime performance from Grammy winner Karol G, bringing Latin flair to Brazil’s NFL showcase.
Predictions
The Chiefs’ continuity at quarterback and tight end should give them the edge, but the offensive line is the X-factor.
Expect Mahomes to lean heavily on quick throws to Kelce and Rashee Rice to neutralize pressure. The Chargers’ offense will flash, but Kansas City’s experience should prevail.
Prediction: Chiefs 27, Chargers 20
How to Watch Chiefs vs. Chargers
Tonight’s game kicks off at 8:00 PM Eastern / 5:00 PM Pacific at Arena Corinthians in São Paulo, Brazil.
The game airs live on YouTube for free here.
It’ll also be broadcast on television in the Chiefs and Chargers markets: KSHB-41 (Kansas City) and KNBC-4 (Los Angeles).
Kansas City Chiefs vs. Los Angeles Chargers
Date: Friday, September 5, 2025
Time: 8:00 PM Eastern / 5:00 PM Pacific
Venue: Arena Corinthians, São Paulo, Brazil
TV: KSHB-41 (KC), KNBC-4 (LA)
Streaming: YouTube
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